ABSTRACT
Renal actinomycosis is a rare infection, and actinomycosis mostly acts as a normal flora in mouth, colon and vagina. We present a case of 56 years old man, who referred to our center for renal transplantation with kidney stone and diagnosed with renal actinomycosis. This case has risen possibility of rare infection that can be considered in the setting of renal transplantation
Subject(s)
Humans , Male , Kidney Calculi , Kidney Transplantation/adverse effects , Kidney Failure, Chronic , C-Reactive ProteinABSTRACT
Diffuse large B-cell lymphoma [DLBCL] is the most common type of lymphoma. There are various types of DLBCL including immunoblastic and centroblastic. Epstein-Barr virus [EBV] is a member of Herpes virus family found in all human populations inducing different lymphoproliferative disorders. The role of EBV in the development of DLBCL is known. Multiple laboratory methods are available for detecting EBV. This study was conducted to determine the correlation of EBV with DLBCL in samples referred to pathology ward in Shariati and Sina Hospitals by chromogenic in situ hybridization [CISH] method. In this case/control study, pathological specimens of 50 patients with DLBCL as well as 50 reactive lymph nodes and tonsils [control group] were collected from archives of Shariati and Sina Hospitals and were evaluated for EBV encoded RNA [EBER] expression based on CISH method. A peptide nucleic acid [PNA] EBV probe [Dakocytomatin] was used while all the processes were done in RNAase-free conditions using RNAase-free water, sterile gloves and samplers. Out of fifty specimens in the case group, eight were positive for EBER in comparison with two in the control group [P=0.046]. No statistically significant difference was observed between intranodal or extranodal samples [P=0.736] or between males and females [P=0.0746]. Our study showed that EBV positivity for EBER in patient with DLBCL could be determined more effectively by CISH method than immunohistochemistry [IHC]. Comparative analysis between CISH, PCR and IHC methods is recommended
Subject(s)
Humans , Epstein-Barr Virus Infections , In Situ HybridizationABSTRACT
The tumors of sella turcica are among the common causes of pituitary enlargement. In selected autopsy series up to 25% of pituitaries have a small incidental micro adenoma. No comprehensive study concerning the prevalence of these tumors has been conducted in Iran previously. In this article the prevalence and distribution of sella turcica tumors in 20 years and more old cadavers dissected in the legal medicine center of Tehran in 1383-1384 have been studied. In this cross-sectional and descriptive observational study, 186 pituitary glands from cadavers dissected during the second half of1383 and throughout 1384 were studied with a view to presence of tumor, type of tumor and size of adenomas and in relation to the age and sex of cadavers. The overall prevalence of pituitary tumors was 10.2% [19 of 186 glands] among which was 4.3% adenoma [8 cases], 4.3% craniopharyngioma [8 cases], and 1.6% meningioma [3 cases]. Maximum prevalence of pituitary tumors [6 cases] was in 3rd decade and then in 8th decade afterwards [5 cases]. The prevalence of pituitary tumor was 11.26% [8 Cases] of 71 cadavers in females and 9.56% [11 Cases] of 115 codavers in males. Among 8 observed tumors in females 5 were craniopharngioma, and 3 adenoma.Among 11 observed tumors in males 5 were adenoma, 3 meningioma, and 3 craniopharyngioma. Among 8 observed adenoma, 7 were microadenoma [diameter less than 10mm] and 1 was macro adenoma [diameter more than I Omm]. In this study, no statistically significant relationship was observed between sex of the cadavers and the prevalence and type of tumors. The overall prevalence of adenoma and craniopharyngioma was equal .The relationship between tumor prevalence and age was statistically significant .Microadenoma was significantly more prevalent than macroadenoma